As a result of COVID-19, disruptions in cross-border trade have led to a “new world” of trade costs. These include new protocols, additional border controls, and new documentation requirements for shippers and traders. At the same time, trade facilitation measures taken at the border have made it possible for supply chains to continue to deliver. Further streamlining of border procedures can be key for helping economies with the next phases of the COVID-19 pandemic including the global production and distribution of a vaccine.